ObjectiveThe primary objective of this systematic review was to evaluate the effectiveness of the simultaneous combination of neural mobilization and traction therapy (SNMCT) in reducing pain and disability for patients with cervical radiculopathy.MethodsWe conducted a systematic review with meta-analysis using the randomized controlled trials (RCTs) articles published in PubMed, Cochrane Library, ...
Emerging evidence suggests that exercise-induced fatigue not only compromises athletic performance but also negatively affects nervous system function. However, effective strategies to prevent or mitigate its adverse neurological consequences remain limited. Using a rat exhaustive exercise training paradigm, this study aims to determine whether intranasal methylene blue (MB) can mitigate neuronal damage ...
Caption-augmented reasoning model with Hierarchical rank LoRA finetuing for medical visual question AnsweringObjective: Medical Visual Question Answering (VQA) is a quintessential application scenario of biomedical Multimodal Large Language Models (MLIMs). Previous studies mainly focused on input image-question pairs, neglecting the rich medical knowledge of the relevant captions of the pretrained ...
Introduction: Tirzepatide (TZP), a dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide 1 receptor agonist, has been showing superior benefits in weight loss and glucose lowering in patients with obesity, while the tissue-specific mechanisms of TZP as well as its side effects remain to be investigated.Objectives: We aimed to explore whether localized injection of TZP into inguinal ...
茶叶的化学组成及含量决定其营养价值,目前茶叶市场出现品质参差不齐、定价不一、溯源困难、品种模糊以及掺假现象频发等问题。本文介绍了当前国内外茶叶化学成分定性和定量分析的主要仪器方法,包括光学、色谱、质谱、色谱-质谱及电化学的电子鼻、电子舌。综述了近年来各方法在茶叶品质评估、产地溯源、品种鉴别、掺伪检测、贮藏年份鉴定中的应用现状,并提出了未来技术的发展方向,为研究者深入理解不同化学组分的分析路径提供了全面参考。...
单链DNA(single-stranded DNA,ssDNA)适配体是通过体外配体指数富集系统进化筛选获得的较短的单链脱氧核糖核苷酸序列。它们能够通过构象变化实现与靶标高亲和力和特异性结合，具有制备简单、成本低、稳定性高、易于修饰和免疫原性低等优点，因此被称为“化学抗体”。ssDNA适配体已在食品安全检测领域显示出巨大潜力。作者综述了基于细胞指数富集配体系统进化（systematic evolution of ligands by exponential enrichment,SELEX）技术发展的ssDNA适配体筛选技术，...
ABSTRACTBACKGROUND: Clostridium botulinum and Clostridium perfringens, 2 major foodborne pathogenic fusobacteria, have a variety of virulent protein types with nervous and enterotoxic pathogenic potential, respectively.OBJECTIVE: The relationship between the molecular evolution of the 2 Clo stridium genomes and virulence proteins was studied via a bioinformatics prediction method. The genetic stability,...
目的 根据广东地区送往广州达安临床检验中心中老年人群体检监测情况，比较分析不同性别和年龄人群尿常规主要指标检测结果，探讨指标变化特点，及时了解尿常规主要指标对中老年人群的健康影响。方法 随机抽取2017年5月至2022年4月广东地区12 450名中老年体检人群尿常规检测数据，选取pH、亚硝酸盐、白细胞、尿隐血和尿葡萄糖5项指标，比较分析不同年龄段和性别间各指标分布差异。结果 性别差异对亚硝酸盐、白细胞和尿隐血3项指标阳性率总体影响较大(...
AbstractThe key to curriculum reform lies in changing the learning style, and establishing a technology platform is an effective method of achieving this reform. This paper analyzes the problems that exist in the current experimental teaching of medical technology and proposes a reform strategy for a mixed teaching system that combines virtual and real methods. This strategy includes team teaching,...
摘要：血管性痴呆（vascular dementia, VaD）患病率高，病理分子机制复杂，现代医学在发病机制、诊断、治疗等方面开展了广泛研究，但目前仍未完全阐明其分子机制，且尚无疗效公认的治疗药物，亟须进一步探索其分子机制及治疗方案。中医治则治法指导中药复方广泛应用于血管性痴呆的临床治疗，具有多靶点、多通路、多层次协同治疗的作用机制，与血管性痴呆复杂的分子机制相契合，具有重要研究价值和广阔临床应用前景。系统综述国内外近年中医药复方干预血管性痴呆的实验研究文献，...
